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solute carrier family 3 member 2  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc solute carrier family 3 member 2
    Solute Carrier Family 3 Member 2, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 44 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/solute+carrier+family+3+member+2/4F2hc%2FCD98+XP+Rabbit+mAb/pm41642374-93-29-68
    Average 95 stars, based on 44 article reviews
    solute carrier family 3 member 2 - by Bioz Stars, 2026-10
    95/100 stars

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    Related Articles

    other:

    Article Title: Combination of sodium pentaborate pentahydrate, curcumin and piperine treatment induces ferroptosis in hepatocellular carcinoma cells by regulating iron homeostasis and ROS activity in vitro.
    Article Snippet: in bone development [5], the central nervous system [6] and the potential as therapeutic agents for cancers such as hepatocellular car [cinoma7], breast cancer [8] and prostate adenocarcinoma [9].. Curcumin (Cur) is a bioactive component derived from the rhizome of Curcuma longa [10].. Several studies have shown that curcumin, which has a wide spectrum of bioactivity, has anti-inflammatory and anti-oxidant [11] properties as well as potential anti-cancer effects [12, 13].

    Incubation:

    Article Title: Yanghe Decoction promotes ferroptosis through PPARγ-dependent autophagy to inhibit the malignant progression of triple-negative breast cancer.
    Article Snippet: Triple-negative breast cancer (TNBC) is a heterogeneous subtype of breast cancer that displays highly aggressive with poor prognosis.. Yanghe Decoction (YHD) has been used in the treatment of breast cancer for many years.. We aimed to explore the effects of YHD on the malignant phenotypes of MDA-MB-231 cells and the potential mechanism related to PPARγ, autophagy and ferroptosis.



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    CGA regulates the relative expression level of ferroptosis proteins after HIBD in newborn mice. (A–F) Western blot of SLC7A11, FHC, FLC, <t>SLC3A2,</t> GLS2, and GSS expression in the cortex ( n = 4). β-Actin was used as an internal reference. (G) Cox-2 , Nrf2 , GSH and GPX4 mRNA levels in hippocampus tissue 24 hours after HIBD; GAPDH mRNA was used as a normalization control ( n = 3). Data are presented as mean ± SEM. * P < 0.05, ** P < 0.01, vs . Sham + NS group; # P < 0.05, ## P < 0.01, vs . HI + NS group (one-way analysis of variance followed by Tukey’s post hoc test). CGA: Chlorogenic acid; COX2: cyclooxygenase-2; FHC: ferritin heavy chain; FLC: ferritin light chain; GAPDH: glyceraldehyde-3-phosphate dehydrogenase; GLS2: glutaminase 2; GSH: L-glutathione; GSS: glutathione synthase; HI or HIBD: hypoxic-ischemic brain injury; Nrf2: nuclear factor (erythroid-derived 2)-like 2; NS: normal saline; SLC3A2: solute carrier <t>family</t> <t>3</t> member 2; SLC7A11: solute carrier family 7 member 11.
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    CGA regulates the relative expression level of ferroptosis proteins after HIBD in newborn mice. (A–F) Western blot of SLC7A11, FHC, FLC, SLC3A2, GLS2, and GSS expression in the cortex ( n = 4). β-Actin was used as an internal reference. (G) Cox-2 , Nrf2 , GSH and GPX4 mRNA levels in hippocampus tissue 24 hours after HIBD; GAPDH mRNA was used as a normalization control ( n = 3). Data are presented as mean ± SEM. * P < 0.05, ** P < 0.01, vs . Sham + NS group; # P < 0.05, ## P < 0.01, vs . HI + NS group (one-way analysis of variance followed by Tukey’s post hoc test). CGA: Chlorogenic acid; COX2: cyclooxygenase-2; FHC: ferritin heavy chain; FLC: ferritin light chain; GAPDH: glyceraldehyde-3-phosphate dehydrogenase; GLS2: glutaminase 2; GSH: L-glutathione; GSS: glutathione synthase; HI or HIBD: hypoxic-ischemic brain injury; Nrf2: nuclear factor (erythroid-derived 2)-like 2; NS: normal saline; SLC3A2: solute carrier family 3 member 2; SLC7A11: solute carrier family 7 member 11.

    Journal: Neural Regeneration Research

    Article Title: Chlorogenic acid alleviates hypoxic-ischemic brain injury in neonatal mice

    doi: 10.4103/1673-5374.350203

    Figure Lengend Snippet: CGA regulates the relative expression level of ferroptosis proteins after HIBD in newborn mice. (A–F) Western blot of SLC7A11, FHC, FLC, SLC3A2, GLS2, and GSS expression in the cortex ( n = 4). β-Actin was used as an internal reference. (G) Cox-2 , Nrf2 , GSH and GPX4 mRNA levels in hippocampus tissue 24 hours after HIBD; GAPDH mRNA was used as a normalization control ( n = 3). Data are presented as mean ± SEM. * P < 0.05, ** P < 0.01, vs . Sham + NS group; # P < 0.05, ## P < 0.01, vs . HI + NS group (one-way analysis of variance followed by Tukey’s post hoc test). CGA: Chlorogenic acid; COX2: cyclooxygenase-2; FHC: ferritin heavy chain; FLC: ferritin light chain; GAPDH: glyceraldehyde-3-phosphate dehydrogenase; GLS2: glutaminase 2; GSH: L-glutathione; GSS: glutathione synthase; HI or HIBD: hypoxic-ischemic brain injury; Nrf2: nuclear factor (erythroid-derived 2)-like 2; NS: normal saline; SLC3A2: solute carrier family 3 member 2; SLC7A11: solute carrier family 7 member 11.

    Article Snippet: The primary antibodies used included rabbit anti-4-hydroxynonenal (4-HNE; 1:2000, Abcam, Cat#ab46545, RRID: AB_722490), rabbit anti-glutathione peroxidase 4 (GPX4; 1:100, ABclonal, Wuhan, China, Cat# a1933, RRID:AB_2763960), rabbit anti-solute carrier family 3 member 2 (SLC3A2; 1:200, ABclonal, Cat# a5702, RRID:AB_2766461), rabbit anti-solute carrier family 7 member 11 (SLC7A11; 1:1000, ABclonal, Cat# a15604, RRID:AB_2763010), rabbit anti-glutaminase 2 (GLS2; 1:1000, ABclonal, Cat# a16029, RRID:AB_2763466), rabbit anti-glutathione synthase (GSS; 1:2000, ABclonal, Cat# a14535, RRID: AB_2861700), rabbit anti-ferritin light chain (FLC; 1:2000, Cat# a11241, ABclonal, RRID:AB_2861532), and rabbit anti-ferritin heavy chain (FHC; 1:2000, ABclonal, Cat# a1144, RRID: AB_2758562).

    Techniques: Expressing, Western Blot, Derivative Assay

    CGA exerts neuroprotection via the system Xc – /GPX4 axis. (A–D) Western blot analysis of SLC3A2, SLC7A11, GSS, and GPX4 in the cortex. β-Actin was used as an internal reference. (E–H) Quantitative analyses of SLC3A2, SLC7A11, GSS, and GPX4 expression normalized with β-actin in the cortex. (I) The MDA level in the cortex. Data are presented as mean ± SEM ( n = 4). * P < 0.05, ** P < 0.01 (one-way analysis of variance followed by Tukey’s post hoc test). CGA: Chlorogenic acid; GPX4: glutathione peroxidase 4; GSS: glutathione synthase; HI or HIBD: hypoxic-ischemic brain injury; MDA: malondialdehyde; SLC3A2: solute carrier family 3 member 2; SLC7A11: solute carrier family 7 member 11.

    Journal: Neural Regeneration Research

    Article Title: Chlorogenic acid alleviates hypoxic-ischemic brain injury in neonatal mice

    doi: 10.4103/1673-5374.350203

    Figure Lengend Snippet: CGA exerts neuroprotection via the system Xc – /GPX4 axis. (A–D) Western blot analysis of SLC3A2, SLC7A11, GSS, and GPX4 in the cortex. β-Actin was used as an internal reference. (E–H) Quantitative analyses of SLC3A2, SLC7A11, GSS, and GPX4 expression normalized with β-actin in the cortex. (I) The MDA level in the cortex. Data are presented as mean ± SEM ( n = 4). * P < 0.05, ** P < 0.01 (one-way analysis of variance followed by Tukey’s post hoc test). CGA: Chlorogenic acid; GPX4: glutathione peroxidase 4; GSS: glutathione synthase; HI or HIBD: hypoxic-ischemic brain injury; MDA: malondialdehyde; SLC3A2: solute carrier family 3 member 2; SLC7A11: solute carrier family 7 member 11.

    Article Snippet: The primary antibodies used included rabbit anti-4-hydroxynonenal (4-HNE; 1:2000, Abcam, Cat#ab46545, RRID: AB_722490), rabbit anti-glutathione peroxidase 4 (GPX4; 1:100, ABclonal, Wuhan, China, Cat# a1933, RRID:AB_2763960), rabbit anti-solute carrier family 3 member 2 (SLC3A2; 1:200, ABclonal, Cat# a5702, RRID:AB_2766461), rabbit anti-solute carrier family 7 member 11 (SLC7A11; 1:1000, ABclonal, Cat# a15604, RRID:AB_2763010), rabbit anti-glutaminase 2 (GLS2; 1:1000, ABclonal, Cat# a16029, RRID:AB_2763466), rabbit anti-glutathione synthase (GSS; 1:2000, ABclonal, Cat# a14535, RRID: AB_2861700), rabbit anti-ferritin light chain (FLC; 1:2000, Cat# a11241, ABclonal, RRID:AB_2861532), and rabbit anti-ferritin heavy chain (FHC; 1:2000, ABclonal, Cat# a1144, RRID: AB_2758562).

    Techniques: Western Blot, Expressing

    Schematic model for the mechanism of CGA in HIE. CGA inhibits ferroptosis by activating the system Xc – /GPX4 axis after HI. CGA: Chlorogenic acid; GCL: glutamate cysteine ligase; GLS: glutaminase; GPX4: glutathione peroxidase 4; GSH: L-glutathione; GSS: glutathione synthase; GSSG: L-glutathione oxidized; HIE: hypoxic-ischemic encephalopathy; ROS: reactive oxygen species; SLC3A2: solute carrier family 3 member 2; SLC7A11: solute carrier family 7 member 11; Xc – : the glutamate/cystine antiporter.

    Journal: Neural Regeneration Research

    Article Title: Chlorogenic acid alleviates hypoxic-ischemic brain injury in neonatal mice

    doi: 10.4103/1673-5374.350203

    Figure Lengend Snippet: Schematic model for the mechanism of CGA in HIE. CGA inhibits ferroptosis by activating the system Xc – /GPX4 axis after HI. CGA: Chlorogenic acid; GCL: glutamate cysteine ligase; GLS: glutaminase; GPX4: glutathione peroxidase 4; GSH: L-glutathione; GSS: glutathione synthase; GSSG: L-glutathione oxidized; HIE: hypoxic-ischemic encephalopathy; ROS: reactive oxygen species; SLC3A2: solute carrier family 3 member 2; SLC7A11: solute carrier family 7 member 11; Xc – : the glutamate/cystine antiporter.

    Article Snippet: The primary antibodies used included rabbit anti-4-hydroxynonenal (4-HNE; 1:2000, Abcam, Cat#ab46545, RRID: AB_722490), rabbit anti-glutathione peroxidase 4 (GPX4; 1:100, ABclonal, Wuhan, China, Cat# a1933, RRID:AB_2763960), rabbit anti-solute carrier family 3 member 2 (SLC3A2; 1:200, ABclonal, Cat# a5702, RRID:AB_2766461), rabbit anti-solute carrier family 7 member 11 (SLC7A11; 1:1000, ABclonal, Cat# a15604, RRID:AB_2763010), rabbit anti-glutaminase 2 (GLS2; 1:1000, ABclonal, Cat# a16029, RRID:AB_2763466), rabbit anti-glutathione synthase (GSS; 1:2000, ABclonal, Cat# a14535, RRID: AB_2861700), rabbit anti-ferritin light chain (FLC; 1:2000, Cat# a11241, ABclonal, RRID:AB_2861532), and rabbit anti-ferritin heavy chain (FHC; 1:2000, ABclonal, Cat# a1144, RRID: AB_2758562).

    Techniques: